Table III.
Dendritic cell phenotype, as determined by flow cytometry.
| Phenotype | |||
|---|---|---|---|
| Treatment group | CD80 (P-value) | CD86 (P-value) | HLA-DR (P-value) |
| Day 6 without stimulation (control group) | 10.12±4.15 (reference) | 19.25±8.76 (reference) | 70.89±8.21 (reference) |
| Day 7 without stimulation (group A) | 16.86±8.05 (P=0.267) | 24.85±11.64 (P=0.542) | 71.62±8.31 (P=0.919) |
| TNF-α-stimulated maturation (group B) | 49.92±9.36 (P=0.003) | 89.68±2.12 (P<0.001) | 89.45±2.81 (P=0.021) |
| Stimulation by the VNTR1 plasmid (group C) | 53.87±8.41 (P=0.001) | 91.29±3.93 (P<0.001) | 90.83±4.91 (P=0.023) |
| TNF-α and VNTR1 plasmid co-stimulation (group D) | 58.63±9.05 (P=0.001) | 92.24±3.27 (P<0.001) | 93.43±3.62 (P=0.012) |
CD, cluster of differentiation; HLA-DR, human leukocyte antigen-antigen D related; TNF-α, tumor necrosis factor-α.