TABLE 2.

Multivariate Analysis: Total Thyroidectomy for Benign Pathology

Variable	OR	95% C. I.	p value
Age > 45 years old	0.91	0.53 – 1.59	0.75
Female gender	2.10	1.00 – 4.45	0.05
Family history of thyroid cancer	0.51	0.25 – 1.07	0.07
TSH ≥ 2.5 (U/mL)	0.83	0.46 – 1.52	0.55
Size ≥ 3 cm	0.65	0.37 – 1.15	0.16
Frozen Section	0.19	0.06 – 0.66	<0.01

Multivariate logistic regression was performed with variables carrying a p value ≤ 0.2 from univariate analysis. Variables shown in bold were significantly associated with over-treatment. Also included in the model was each cytologic diagnosis, except for AUS/FLUS which was dropped due to collinearity. None of the cytologic diagnoses were significant. U = units, mL = millimeters, cm = centimeters.