Table 3.
Multivariate logistic regression models relating predictors to willingness to donate brain. Results are presented as odds ratios (OR) and 95% confidence intervals (CI).
| Model 1 Demographics only |
Model 2 Demographics + Religion |
Model 3 Demographics + Family |
Model 4 Demographics + Research knowledge & concerns |
Model 5 Demographics + significant covariates |
|
|---|---|---|---|---|---|
| Variables | OR (95% CI) | OR (95% CI) | OR (95% CI) |
OR (95% CI) | OR (95% CI) |
| Demographics | |||||
| Age, yrs |
1.03 (1.01 – 1.06) |
1.06 (1.02 – 1.10) |
1.03 (1.00 – 1.07) |
1.03 (0.99 – 1.07) |
1.06 (1.02 – 1.11) |
| Female vs. Male |
0.98 (0.61 – 1.59) |
0.87 (0.44 – 1.74) |
0.66 (0.35 – 1.25) |
0.70 (0.38 – 1.30) | 0.50 (0.23 – 1.06) |
| Living alone vs. not alone |
0.62 (0.40 – 0.98) |
0.53 (0.29 – 0.99) |
0.80 (0.41 – 1.56) |
0.56 (0.31 – 0.98) | 0.51 (0.25 – 1.04) |
| Race/ethnicity | |||||
| White | reference | reference | reference | reference | Reference |
| Black |
0.25 (0.15 – 0.40) |
0.28 (0.14 – 0.56) |
0.34 (0.18 – 0.62) |
0.41 (0.21 – 0.80) |
0.41 (0.19 – 0.85) |
| Hispanic | 0.96 (0.48 – 1.94) |
1.01 (0.36 – 2.84) |
1.87 (0.73 – 4.83) |
1.73 (0.75 – 4.01) |
3.38 (1.12 – 10.21) |
| Asian |
0.39 (0.20 – 0.77) |
0.68 (0.25 – 1.82) |
0.60 (0.26 – 1.40) |
0.85 (0.34 – 2.09) | 0.77 (0.29 – 2.05) |
| Religion | |||||
| Catholic Religion vs. other |
-- | 1.68 (0.73 – 3.91) |
-- | -- | -- |
| Arranged for cremation vs. not |
-- |
2.32 (1.13 – 4.73) |
-- | -- | 1.53 (0.73 – 3.21) |
| Body should remain whole |
-- |
0.12 (0.06 – 0.27) |
-- | -- |
0.24 (0.10 – 0.60) |
| Plans for open casket vs. none |
-- | 1.06 (0.54 – 2.07) |
-- | -- | -- |
| Religiosity | -- | 0.91 (0.80 – 1.03) |
-- | -- | -- |
| Family | |||||
| Most likely to discuss with spouse vs. not |
-- | -- | 1.23 (0.60 – 2.52) |
-- | -- |
| Supportive person vs. no |
-- | -- |
6.60 (3.83 – 11.35) |
-- |
5.70 (3.00 – 10.85) |
| Donation is mostly a personal decision vs. family decision |
-- | -- |
1.90 (1.04 – 3.50) |
-- | 1.05 (0.48 – 2.26) |
| Family trusts medical researchers vs. no |
-- | -- | 0.91 (0.53 – 1.56) |
-- | -- |
|
Research knowledge & concerns |
|||||
| Years followed at ADC |
-- | -- | -- | 1.04 (0.98 – 1.11) | -- |
|
Primary reason for participating in research: |
|||||
| To help future generations |
-- | -- | -- | 1.68 (0.99 – 2.85) | -- |
| Concern about body's appearance |
-- | -- | -- | 0.48 (0.20 – 1.13) | -- |
| Concern researchers will not be respectful |
-- | -- | -- | 0.36 (0.19 – 0.70) |
0.27 (0.14 – 0.54) |
| Trust medical researchers |
-- | -- | -- | 1.52 (0.79 – 2.92) | -- |
| Understand what researchers will do with brain |
-- | -- | -- | 2.01 (1.12 – 3.62) |
2.20 (1.14 – 4.24) |
| Understand what to do ahead of time |
-- | -- | -- | 2.22 (1.25 – 3.96) |
2.19 (1.13 – 4.24) |
| More info would be helpful |
-- | -- | -- | 0.94 (0.55 – 1.62) | -- |