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Regions showing reduced fractional anisotropy (FA) in medication-free patients with major depressive disorder (MDD) compared with healthy controls (HC). Fractional anisotropy changes in patients are displayed on a 3-dimensionally rendered brain, with part of the left or right hemisphere removed. CC = corpus callosum; CHL = cerebellum hemispheric lobule; L = left; R = right; SLF = superior longitudinal fasciculus.
