Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2017 Jan 25;13(3):1563–1568. doi: 10.3892/ol.2017.5651

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright: © Shen et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

PMC Copyright notice

Figure 4. — TDZ suppressed tumor initiation and growth in vivo. (A) Comparison of tumor initiating ability on A549 sphere cells pre-treated with DMSO or TDZ (1 or 10 µM). The number of tumors was plotted against time following inoculation (day 0). The incidence indicated the number of mice with palpable tumor. (B) Growth curve of subcutaneous tumors with the indicated pre-treatment. (C) Tumor morphology with different treatments on day 51. (D) Measurement of tumor weights with indicated treatments on day 51. Tumor volume was measured every 3 days and the data shown represent the mean ± SD or mean + SD (n=6). The number of mice for each type of treatment was 6. *P<0.05, **P<0.01. TDZ, thioridazine; DMSO, dimethyl sulfoxide; SD, standard deviation; TDZ-1, thioridazine 1 µM; TDZ-10, thioridazine 10 µM.