Amount of (A) PDGF-AB, (B) IGF-1, (C) PDGF-BB and (D) HGF in plasma. Each number corresponds to a chitosan sample defined in Table I. Values are expressed as the mean ± standard deviation (n=4). *P<0.0001, **P<0.0005, ***P<0.001 vs. b. #P<0.0005, ##P<0.05 vs. all other samples. PDGF, platelet-derived growth factor; IGF, insulin growth factor; HGF, hepatocyte growth factor; b, blank.