Table I.
EC samples immunohistochemically stained for EphB4 and ephrin-B2 according to ER/PR expression level.
| ER/PR expression EC group, no. of patients (%) | ||||||
|---|---|---|---|---|---|---|
| IHC staining | ER−/PR− (n=11) | ER+/PR+/+++ (n=13) | ER++/+++/PR+/+++ (n=20) | |||
| EphB4 | ||||||
| − | 9 (81.82) | 0 (0) | 0 (0) | |||
| + | 2 (18.18) | 6 (46.15) | 1 (5) | |||
| ++/+++ | 0 (0) | 7 (53.85) | 19 (95) | |||
| Ephrin-B2 | ||||||
| − | 9 (81.82) | 8 (61.54) | 0 (0) | |||
| + | 2 (18.18) | 4 (30.77) | 1 (5) | |||
| ++/+++ | 0 (0) | 1 (7.69) | 19 (95) | |||
EphB4, erythropoietin-producing hepatocyte receptor B4; ER, estrogen receptor; PR, progesterone receptor; EC, endometrium carcinoma; IHC, immunohistochemistry.