Table 1.

Results after treatment with ²¹³Bi-MX35 and unlabeled MX35

Group	Treatment	Activity concentration	Macroscopic tumor (no. of animals)	Microscopic tumor (no. of animals)	Ascites (no. of animals)	TFF
1	213Bi-MX35	3 MBq/mL	4/20	9/20	0	0.55
2	213Bi-MX35	9 MBq/mL	1/18a	4/18a	0	0.78
3	Ref. group (cold MX35)	–	7/20	17/20	4	0.15

TFF tumor-free fraction, i.e., fraction of the mouse groups with no macroscopic or microscopic tumors and no ascites

^aTwo animals were excluded from the mouse group receiving 9 MBq/mL; one was sacrificed earlier because of atypical mouse behavior (no tumor tissue could be detected), and one was excluded because of a sole subcutaneous tumor outside of the peritoneum which was suspected to be the result of cell leakage from the peritoneal cavity post inoculation