Table 2.
Changes of QoL, anxiety and depression parameters level (median %, in brackets standard deviation). Friedman (X2) ANOVA test used for statistical analysis.
| Before SABR | 2 w. after | 14 w. after | p value | Change | |
|---|---|---|---|---|---|
| QLQ-C30 | |||||
| Global health | 58.5 (18.9) | 63 (17) | 64 (17.5) | 0.025 | ↑ |
| Physical functioning | 66 (21.5) | 70.2 (19.6) | 73 (16.9) | 0.032 | ↑ |
| Role functioning | 84 (27.1) | 87.2 (21.8) | 86.3 (25) | 0.82 | – |
| Emotional functioning | 73.7 (24.8) | 78.9 (50) | 82.7 (21) | 0.0003 | ↑ |
| Cognitive functioning | 80.7 (22.7) | 82.9 (22.7) | 84.6 (20.3) | 0.14 | – |
| Social functioning | 79.9 (21) | 83.3 (19.9) | 85 (18) | 0.15 | – |
| Fatigue | 32 (28.9) | 31.1 (25.6) | 25.3 (18.9) | 0.49 | – |
| Nausea | 1.3 (4.5) | 2.5 (6.1) | 0.8 (3.7) | 0.23 | – |
| Pain | 23.1 (26) | 17.9 (24.3) | 15.8 (20.9) | 0.18 | – |
| Dyspnea | 33.3 (32.4) | 29.1 (28.8) | 28.2 (25.9) | 0.27 | – |
| Insomnia | 40.2 (33.5) | 26.5 (33.5) | 23.9 (28.5) | 0.003 | ↓ |
| Appetite loss | 18.8 (26.3) | 18.8 (30) | 11.1 (20.7) | 0.03 | – |
| Constipation | 27.3 (33.2) | 19.6 (30.2) | 12.9 (23.7) | 0.002 | ↓ |
| Diarrhea | 1.7 (7.4) | 1.7 (7.4) | 2.5 (8.9) | 0.71 | – |
| Financial problems | 17.1 (26) | 14.5 (22.7) | 14.5 (18.4) | 0.91 | – |
| QLQ-LC13 | |||||
| Dyspnea | 37.0 (25) | 33.0 (25) | 32.0 (23.2) | 0.027 | –/↓ |
| Coughing | 35.8 (27.6) | 37.0 (29.1) | 29.1 (24.1) | 0.19 | – |
| Hemoptysis | 0.8 (5.2) | 1.6 (7.3) | 0.0 (NA) | NA | – |
| Sore mouth | 5.8 (19.1) | 5.8 (17) | 0.0 (NA) | 0.06 | – |
| Dysphagia | 8.3 (19.6) | 7.5 (22) | 6.7 (21) | 0.25 | – |
| Neuropathy | 24.1 (29) | 20.1 (29) | 23.3 (26) | 0.50 | – |
| Alopecia | 15.8 (30.1) | 5.8 (21.2) | 7.5 (20.6) | 0.06 | – |
| Pain in chest | 19.1 (26.3) | 15.0 (22.6) | 15.0 (16.7) | 0.41 | – |
| Pain arm | 24.2 (30.1) | 14.2 (22.5) | 14.2 (22.5) | 0.02 | –/↓ |
| Pain in other | 23.3 (31.3) | 21.7 (24.5) | 15.9 (26.1) | 0.19 | – |
| HAD-S | |||||
| Anxiety | 4.8 (4.5) | 3.6 (3.5) | 3.3 (3.4) | 0.0063 | ↓ |
| Depression | 4.5 (3.7) | 3.0 (3.4) | 2.84 (3.6) | 0.0016 | ↓ |
Bold values indicate statistically significant changes at p < 0.05.