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NK cells contribution to graft-versus-host-disease (GvHD) protection or induction. Immunological interactions leading to GvHD protective (left panel) or promoting (right panel) effect of NK cells. Donor immune cells are depicted in blue while host target cells are depicted in orange. NK, natural killer; T, T lymphocyte; APC, antigen-presenting cell; IFN-γ, interferon-γ; TNF-α, tumor necrosis factor-α.
