Table 1.
Examples of InnateDB-curated molecular interactions generated from DEG demonstrated during the acute stage of ovine F. hepatica infection (week 1 postinfection).
| Query Xref | Query name | Interactions | Full name | Interaction type | Tissue | Cell type | PMIDa | Source database ID |
|---|---|---|---|---|---|---|---|---|
| ENSG00000141510 | TP53 | TLR10:TP53 | TLR10 interacts with TP53 | Transcriptional regulation | Peripheral blood | T cell | 21483755 | IDB-224139 |
| ENSG00000141510 | TP53 | TLR6:TP53 | TLR6 interacts with TP53 | Transcriptional regulation | Peripheral blood | T cell | 21483755 | IDB-224137 |
| ENSG00000184216 | IRAK1 | NLRP12:IRAK1 | NLRP12 physically interacts with IRAK1 | Physical interaction | Peripheral blood, kidney cell line | Monocyte | 16203735 | IDB-113695; IDB-114001 |
| ENSG00000184216 | IRAK1 | ITGAM:IRAK1 | ITGAM physically interacts with IRAK1 | Physical interaction | Peripheral blood, kidney cell line | Monocyte | 11701612 | IDB-113998; IDB-113999 |
| ENSG00000141968 | VAV1 | IL6ST:VAV1 | IL6ST interacts with VAV1 | Physical association | Plasmacytoma cell line | B-cell | 9013873 | IDB-156849 |
| ENSG00000136634 | IL10 | IRF5:IL10 | IRF5 interacts with IL10 | Transcriptional regulation | Peripheral blood | Macrophage | 21240265 | IDB-223555 |
aPMID refers to the publication that reported the interaction evidence that refers to the experimental procedures and conditions to support the interactions.