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Effect of pinoresinol (14) on the surface expression of P-glycoprotein by flow cytometric analysis. (A) Lucena 1 and (B) K562 cells were stained with FITC-labeled mouse anti-human P-glycoprotein antibody at 24 and 48 h. Unstained cells are shown with red histogram, stained cells with blue histogram and cells stained and treated with 14 at 112 μM are shown with green histogram. Histograms are representative of three independent experiments.
