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. 2017 Apr 25;7:46759. doi: 10.1038/srep46759

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NADPH nitroreductase may enhance the oxidation capacity of K. vulgare and the contents of 2-keto-gluconic acid, 2-keto-L-gulonic acid and D-gluconic acid in K. vulgare, which was further enhanced during long-term adaptation. The mutation of NADPH-dependent FMN reductase and trehalose operon repressor TreR in B150 may affect the supply of flavin and trehalose, thus taking part in the anti-oxidation.