Table 2.
Licensed aP and wP vaccines in the world.*
| type | Brand® | Manufacturer | Contents of pertussis antigens per dose | Adjuvant (mg-Al3+ content) | Reference |
|---|---|---|---|---|---|
| DTap | Hexavac | Sanofi Pasteur | PT 25 μg; | aluminum hydroxide 0.3 mg | 34,132,133 |
| FHA 25 μg | |||||
| Tetravac(DTap-IPV) | |||||
| Pentaxim (DTaP-IPV//PRP-T) | |||||
| Infanrix/Pediarix | GlaxoSmithKline Biologicals | PT 25 μg; | aluminum hydroxide 0.5 mg | 34 | |
| FHA 25 μg; | |||||
| PRN 8 μg | |||||
| Pediacel/Pentacle (DTap-IPV-Hib) | Sanofi Pasteur | PT 20μg; | aluminum phosphate 1.5 mg | 134,135 | |
| FHA 20 μg; | |||||
| Quadracel (DTap-IPV) | |||||
| PRN 3 μg; | |||||
| FIM 2/3 5 μg | |||||
| Daptacel | Sanofi Pasteur | PT 10 μg; | aluminum phosphate 0.33 mg | 28,136 | |
| FHA 5 μg; | |||||
| PRN 3 μg; | |||||
| FIM 2/3 5 μg | |||||
| Tripacel | |||||
| Tdap | Boostrix | GlaxoSmithKline Biologicals | PT 8 μg; | Aluminum hydroxide ≤ 0.39 mg (US) or 0.5 mg (rest of world) | 34,137 |
| FHA 8 μg; | |||||
| PRN 2.5 μg | |||||
| Adacel, | Sanofi Pasteur | PT 2.5 μg; | Aluminum phosphate 0.33 mg | 132,136,137 | |
| Triaxis | FHA 5 μg; | ||||
| Covaxis(Tdap+OPV) | PRN 3 μg; | ||||
| Repevax (Tdap-IPV) | FIM 2/3 5 μg | ||||
| diTeKiBooster | Serum Institute of India Ltd. | PT 20 μg | Aluminum hydroxide 0.5 mg | 136 | |
| wP | Triple Antigen | Serum Institute of India Ltd. | Whole-cell B. pertussis ≥ 4 IU | aluminum phosphate ≤ 1.25 mg | 28,138 |
| Pentavac (DTwP-HepB+Hib) | |||||
| DT-COQ | Sanofi Pasteur | Whole-cell B. pertussis ≥ 4 IU | aluminum hydroxide 0.6 mg | 28 | |
| Quinvaxem | Crucell-Janssen | Whole-cell B. pertussis ≥ 4 IU | aluminum phosphate 0.3 mg | 28 | |
| DTwP | GlaxoSmithKline Biologicals | Whole-cell B. pertussis ≥ 2 IU | 137 |
*
The table does not represent all worldwide licensed pertussis vaccines.