Table 3.
Burden of seasonal influenza in Canada expressed as probabilities of outcomes.
| Source | Disease | Population | Age (years) | p(antiviral|flu) | p(antibiotics|flu) | p(hosp|flu) | p(ICU|flu) | p(MV|flu) |
|---|---|---|---|---|---|---|---|---|
| Fanella 201163 | Seasonal influenza A or B | — | Under 18 years; median = 1.08 | 13.0% | — | — | 26.1% | 66.0% |
| Moore 200660 | Influenza | — | Children; median = 1.7 | 7.0% | 77.0% | — | 12.0% | 6.2% |
| Tran 201234 | Seasonal influenza A | Hospitalized | Children; mean = 3.4 | 6.1% | 69.9% | — | 12.7% | 54.5% |
| Aguirre 201143 | Seasonal influenza A | — | Under 18 years; mean = 5.6 | 5.0% | — | 35.0% | 0.9% | — |
| CCDR 200661 | Influenza | — | Under 17 years | 6.6% | 69.3% | — | 12.3% | 6.4% |
| Mitchell 201336 | Influenza | During pH1N1 | Mean = 46.5 | 89.6% | 76.9% | — | 25.7% | — |
| Mitchell 201336 | Influenza | Pre-H1N1 | Mean = 66.1 | 39.8% | 65.7% | — | 12.6% | — |
| Mitchell 201336 | Influenza | Post-pH1N1 | Mean = 69.7 | 79.9% | 75.0% | — | 12.6% | — |
| Wilkinson 201040 | Seasonal influenza A or B | — | Mean = 57.0 | 42.0% | 82.0% | — | −2006/07 or 2007/08: 9.0% −2008/09: 30.0% | — |
| Hassan 201239 | Influenza | 15-day mortality Hospitalized | Median = 65.0 | 66.0% | 91.0% | — | — | 55.0% |
| McGeer 200926 | Influenza | Community-acquired | Mean = 67.0 | 29.0% | — | — | 9.0% | — |
| McGeer 200926 | Influenza | Hospital-acquired | Mean = 67.0 | 75.0% | — | — | 9.0% | — |
| McGeer 200935 | Influenza | ICU admission | Median = 73.0 | 40.0% | 90.0% | — | — | — |
| McGeer 201227 | Influenza | Hospitalized; post-pH1N1 | Median = 76.0 | 72.0% | 84.0% | — | 19.0% | 9.4% |
| McGeer 201227 | Influenza | Hospitalized; pre-pH1N1 | Median = 77.0 | 39.0% | 82.0% | — | 19.0% | 11.0% |
| McGeer 200724 | Influenza | Hospitalized | Adults; mean = 77.2 | 32.0% | 89.0% | — | 16.0% | — |
| McGeer 200724 | Influenza | Hospitalized | Under 15 years | — | — | — | 1.0% | — |
| Church 200228 | Influenza A | — | Elderly; mean = 82.0 | 69.2% | 53.5% | 1.30% | — | — |
| Bowles 200229 | Influenza A/H3N2/Sydney/05/97 | LTC | Elderly | — | 35.0% | 11.0% | — | — |
| O'Riordan 201042 | Seasonal influenza A | Hospitalized | Children; median = 3.3 | — | — | — | 14.0% | – 10.0%– ICU: 68.0% |
| Pollock 201237 | pH1N1 or ILI | Remote FN region | Mean = 6.1 | — | — | 16.1% | — | — |
| Cutler 200956 | ILI | Mean = 20.1 | — | — | 0.0% | — | — |
Note: flu, influenza; hosp, hospitalization; FN, First Nations; ICU, intensive care unit; ILI, influenza-like illness, LTC, long-term care; MV, mechanical ventilation; NR, not reported; pH1N1, pandemic influenza A(H1N1)pdm2009.