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. 2017 Apr 20;12:3281–3294. doi: 10.2147/IJN.S134379

Table S2.

Biodistribution of 89Zr-FA-DFO-liposome, 89Zr-DFO-liposome, and 89Zr-DFO in KB tumor xenograft-bearing CD1 nude mice (n=3) at 48 h post-i.v. injection and 89Zr-PEG-DFO-liposome in healthy CD1 mice (n=3) at 48 h post-i.v. injection expressed as % ID/g

Organ 89Zr-FA-DFO-liposome (n=3) 89Zr-DFO-liposome (n=3) 89Zr-DFO (n=3) 89Zr-PEG-DFO-liposome (n=3)
Blood 0.087±0.103 0.146±0.079 N/A 0.137±0.120
Liver 0.570±0.226 1.083±0.559 0.201±0.054 0.520±0.162
Heart 0.093±0.073 0.215±0.099 0.018±0.005 0.156±0.090
Kidney 3.926±2.898 1.321±0.117 2.054±0.275 4.872±2.161
Colon 0.105±0.065 0.526±0.700 0.204±0.154 0.309±0.206
Lung 0.203±0.142 0.328±0.112 0.209±0.231 0.142±0.067
Muscle 0.051±0.042 0.093±0.037 0.058±0.037 0.063±0.018
Spleen 0.377±0.227 1.639±0.141 0.050±0.006 0.445±0.262
Stomach 0.120±0.092 0.203±0.090 0.169±0.078 0.391±0.311
Bone 2.516±1.704 10.857±5.283 0.121±0.035 2.198±0.473
Small intestine 0.105±0.067 0.144±0.055 0.126±0.073 0.283±0.191
Tumor 0.588±0.518 1.533±0.552 0.069±0.019 N/A

Note: Data presented as mean ± standard deviation.

Abbreviations: FA, folic acid; DFO, deferoxamine; i.v., intravenous; PEG, polyethylene glycol; ID, injected dose; N/A, not available.