TABLE 1.
Average sum of squared slopes for different heart rate correction methods for QTc across treatmentsa
| Treatment | Slope estimate (mean of squared individual slopes) |
||
|---|---|---|---|
| QTcF | QTcI | QTci | |
| Gepotidacin 1,000 mg i.v. 2 h | 0.0023 | 0.0025 | 0.0038 |
| Gepotidacin 1,800 mg i.v. 2 h | 0.0049 | 0.0066 | 0.0092 |
| Moxifloxacin 400-mg tablet | 0.0024 | 0.0024 | 0.0022 |
| Placebo | 0.0017 | 0.0018 | 0.0016 |
As proposed in the publication by Tornoe et al. (6).