TABLE 3.
Additional ISApl1 insertion sites in clinical isolates
| Positiona | TSDb | Strain(s) | Effectc |
|---|---|---|---|
| 1.252 | AT | All isolates | Interruption of iraM (encoding an antiadapter protein) |
| 1.855 | CC | 346595 | Interruption of a hypothetical protein gene (encoding an E. coli YdiK-like protein) |
| 1.915 | GC | 346638 | Interruption of an astB-like gene (encoding succinylarginine dihydrolase) |
| 3.101 | CC | 346638 | Interruption of an araB-like gene (encoding sugar kinase) |
| 3.341 | CA | 346638 | Intergenic |
| 4.758 | TG | 346638 | Intergenic |
| IncFII | GG | 346595 | Intergenic |
| IncI1 | AG | 346355, 346595 | Intergenic |
| IncI2 | AG | 346355 | Interruption of ycfA (encoding HicA toxin) |
a
Chromosomal (numbers) or plasmid (Inc type) location of ISApl1 insertion site. Numbers indicate positions, in megabases, with reference to the origin of chromosomal replication (oriC).
b
Two-base-pair target site duplication (TSD) flanking the site of ISApl1 insertion.
c
Predicted phenotypic change resulting from ISApl1 insertion at the designated location. “Intergenic” implies insertion in a region with no predicted open reading frames.