TABLE 1.
MIC values for the E. coli clinical isolates and the E. coli ErtR (pOmpR-WT) recombinant clone
| β-Lactama | MIC (μg/ml) for: |
|||
|---|---|---|---|---|
| E. coli ErtS | E. coli ErtR | E. coli ErtR MH-CLAVb | E. coli ErtR (pOmpR-WT) | |
| Amoxicillin | >32 | >32 | 32 | >32 |
| Amoxicillin-CLAV | 8 | 16 | ND | 8 |
| Piperacillin | >32 | >32 | 4 | >32 |
| Piperacillin-TZB | 4 | 16 | ND | 4 |
| Temocillin | 2 | 4 | 2 | 2 |
| Cefoxitin | 4 | 16 | 4 | 4 |
| Ceftazidime | 16 | 64 | 0.5 | 16 |
| Ceftazidime-avibactam | 0.125 | 0.25 | ND | 0.125 |
| Cefepime | >32 | >32 | 1 | >32 |
| Aztreonam | >32 | >32 | 0.5 | >32 |
| Ertapenem | 0.032 | 1 | 0.032 | 0.032 |
| Imipenem | 0.125 | 0.25 | 0.125 | 0.125 |
| Meropenem | 0.032 | 0.25 | 0.032 | 0.032 |
a
CLAV, clavulanic acid at 2 μg/ml; TZB, tazobactam at 4 μg/ml.
b
MH-CLAV, MICs obtained using clavulanate (2 μg/ml)-containing Mueller-Hinton agar plates. ND, not determined.