TABLE 2.
Strain/plasmida | Median MIC (μg/ml)b |
|
---|---|---|
Without cCF10 | With cCF10 | |
E. faecium | ||
Wild type/vector | 128 | 128 |
ΔcroRSEfm mutant/vector | 2 | 2 |
ΔcroRSEfm mutant/croRSEfm | 2 | 16 |
E. faecalis | ||
Wild type/vector | 128 | 128 |
ΔcroRSEfs mutant/vector | 8 | 8 |
ΔcroRSEfs mutant/croRSEfm | 8 | 128 |
The strains and plasmids analyzed were as follows: wild-type E. faecium, 1,141,733; E. faecium ΔcroRS mutant, JL537, wild-type E. faecalis, OG1; E. faecalis ΔcroRS mutant, SB35; vector, pJLL105; and croRSEfm, pJLL160.
Median MICs are reported from ≥2 biological replicates.