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Screening of transepithelial transport of PAS via ABC transporters. The rate of transport of 10 μM PAS in the apical-to-basal and basal-to-apical directions in monolayers of LLCPK cells overexpressing P-gp, LLCPK cells overexpressing BCRP, MDCKII cells overexpressing MRP1, and MDCKII cells overexpressing MRP2 is shown. Each data point presents the mean ± SD from three or more independent experiments.
