Table 2. Trans-ancestry genetic correlations between East Asian and European MDD subtypes.
| Traita | ρgb | Pρg>0 | Pρg<1 |
|---|---|---|---|
| Lifetime MDD | 0.332 (0.270, 0.394) | 7.23 × 10−26 | 1.40 × 10−99 |
| Female-only MDD | 0.402 (0.326, 0.477) | 2.04 × 10−25 | 2.59 × 10−54 |
| Recurrent MDD | 0.410 (0.343, 0.477) | 5.40 × 10−33 | 2.23 × 10−66 |
Abbreviation: MDD, major depressive disorder.
a
European prevalences of lifetime, females-only and recurrent MDD were assumed to be 0.15, 0.20 and 0.105, respectively; prevalence of recurrent MDD among Chinese women was assumed to be 0.08.
b
Estimates of ρg are displayed with corresponding 95% confidence intervals.