Table 4.
Average influenza-related events and associated costs (in 2014 US$) avoided by using QIV instead of TIV over the study period, per 100,000 person-years.
| Brazil (2010–2014) | |||||
|---|---|---|---|---|---|
| Young children (6–59 months) | Adults 18–49 y with RF | Adults 50–59 y with RF | Elderly (60 y and older) | Total | |
| Outcomes | |||||
| Influenza cases avoided | 599 | 25 | 33 | 141 | 168 |
| GP consultations avoided | 287 | 16 | 20 | 89 | 89 |
| Lost working days avoided | 244 | 21 | 56 | 148 | 107 |
| Hospitalizations avoided | 8.4 | 0.1 | 0.6 | 4.9 | 3.2 |
| Deaths avoided | 0.02 | 0.00 | 0.04 | 1.17 | 0.38 |
| Influenza-associated costs | |||||
| Direct costs avoided (Third-Party Payer perspective) | $5,065 | $108 | $527 | $3,353 | $2,094 |
| Productivity loss | $7,529 | $654 | $2,319 | $6,955 | $4,106 |
| Total costs avoided (Societal perspective) | $12,594 | $761 | $2,845 | $10,308 | $6,200 |
| Colombia (2007–2014, 2009 excluded) | |||||
| |
Young children (6–23 months) |
Adults 18–49 y with RF |
Adults 50–59 y with RF |
Elderly (60 y and older) |
Total |
| Outcomes | |||||
| Influenza cases avoided | 178 | 16 | 16 | 18 | 34 |
| GP consultations avoided | 72–112 | 9–13 | 7–13 | 3–16 | 13–25 |
| Lost working days avoided | 63–99 | 12–19 | 20–38 | 4–21 | 15–30 |
| Hospitalizations avoided | 4.5–38.3 | 0.0–1.0 | 0.1–4.6 | 0.2–9.7 | 0.6–8.9 |
| Deaths avoided | 0.02–0.19 | 0.00–0.04 | 0.04–0.55 | 0.08–4.00 | 0.04–1.74 |
| Influenza-associated costs | |||||
| Direct costs avoided (Third-Party Payer perspective) | $4,445–$24,067 | $248–$1,699 | $305–$8,477 | $601–$20,027 | $837–$12,355 |
| Productivity loss | $651–$1,014 | $128–$192 | $208–$389 | $40–$217 | $155–$311 |
| Total costs avoided (Societal perspective) | $5,096–$25,081 | $376–$1,891 | $513–$8,866 | $641–$20,245 | $992–$12,666 |
| Panama (2006–2014, 2009 excluded) | |||||
| |
Young children (6–59 months) |
Adults 18–49 y with RF |
Adults 50–59 y with RF |
Elderly (60 y and older) |
Total |
| Outcomes | |||||
| Influenza cases avoided | 201 | 86 | 83 | 77 | 113 |
| GP consultations avoided | 100–124 | 40–70 | 39–67 | 38–65 | 55–82 |
| Lost working days avoided | 90–111 | 57–99 | 113–192 | 59–101 | 71–111 |
| Hospitalizations avoided | 0.7–42.2 | 0.1–5.4 | 0.1–23.8 | 0.7–40.1 | 0.5–27.8 |
| Deaths avoided | 0.03–0.24 | 0.01–0.23 | 0.02–3.36 | 0.20–19.82 | 0.08–6.87 |
| Influenza-associated costs | |||||
| Direct costs avoided (Third-Party Payer perspective) | $1,744–$33,353 | $538–$6,075 | $638–$29,156 | $1,401–$54,162 | $1,138–$30,795 |
| Productivity loss | $2,349–$2,896 | $1,479–$2,580 | $2,956–$5,009 | $1,542–$2,629 | $1,858–$2,899 |
| Total costs avoided (Societal perspective) | $4,093–$36,250 | $2,017–$8,655 | $3,593–$34,165 | $2,942–$56,791 | $2,996–$33,694 |
RF: Risk factor
*
Colombia and Panama: results are presented as a range using the 2 sets of values presented in Table 1.