Table 3.
Associations between telomere length and characteristics of patients at baseline (n = 181)
Univariate | Adjusted for age and sex | |||||
---|---|---|---|---|---|---|
Variables | β | P-valuea | 95% CI | β | P-valuea | 95% CI |
Age | −0.04 | <0.001 | −0.006; −0.003 | |||
Female vs male | 0.06 | 0.04 | 0.003; 0.11 | |||
BMI | ||||||
Underweight | 0.13 | 0.15 | −0.04; 0.30 | 0.08 | 0.33 | −0.08; 0.24 |
Normal weight | Ref | Ref | ||||
Overweight | −0.05 | 0.01 | −0.10; −0.01 | −0.04 | 0.04 | −0.08; −0.001 |
Obese | −0.03 | 0.20 | −0.08; 0.02 | −0.02 | 0.30 | −0.07; 0.02 |
Smoking status (yes vs no) | −0.002 | 0.94 | −0.05; 0.05 | −0.007 | 0.78 | −0.05; 0.04 |
Alcohol status | ||||||
Standard size drinks per week | ||||||
< 1 | Ref | Ref | ||||
1–4 | 0.02 | 0.37 | −0.02; 0.06 | 0.02 | 0.36 | −0.02; 0.06 |
> =5 | 0.04 | 0.15 | −0.01; 0.10 | 0.05 | 0.08 | −0.006; 0.10 |
Education | ||||||
Low | −0.07 | 0.04 | −0.14; −0.002 | −0.03 | 0.41 | −0.09; 0.04 |
Middle | −0.04 | 0.04 | −0.08; −0.002 | −0.03 | 0.15 | −0.06; 0.009 |
High | Ref | Ref | ||||
Pharmacotherapyb (yes vs no) | −0.005 | 0.79 | −0.04; 0.03 | −0.007 | 0.68 | −0.04; 0.03 |
MADRS-S | 0.002 | 0.11 | −0.0005; 0.004 | 0.002 | 0.19 | −0.00007; 0.004 |
HAD-D | 0.002 | 0.45 | −0.003; 0.007 | 0.003 | 0.16 | −0.001; 0.008 |
HAD-A | 0.004 | 0.12 | −0.001; 0.009 | 0.001 | 0.66 | −0.004; 0.006 |
PHQ-9 | 0.003 | 0.05 | −0.00005; 0.006 | 0.002 | 0.13 | −0.0006; 0.005 |
aAssociation tested by a linear regression model
bAntidepressants and/or tranquilizers