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. Author manuscript; available in PMC: 2018 Mar 1.
Published in final edited form as: JAMA Ophthalmol. 2017 Mar 1;135(3):225–231. doi: 10.1001/jamaophthalmol.2016.5551

Table 2.

Agreement between symptom report on a questionnaire compared to documentation in the medical record for the sample of 162 subjects

MR Symptom Documentation
ESQ Symptom Self-Report Presentd
freq (%)
Absente
freq (%)
Kappa (95% CI) McNemar’s Test P-value Holm’s Adjusted P-value
Blurry Visiona,b
 Present 60 (37.5) 25 (15.6) 0.32 (0.17,0.47) 0.586 0.586
 Absent 29 (18.1) 46 (28.8)
Glarea
 Present 5 (3.1) 71 (43.8) −0.02 (−0.10,0.07) <0.001 <0.001
 Absent 7 (4.3) 79 (48.8)
Eye Painc
 Present 34 (21.0) 32 (19.8) 0.42 (0.28,0.56) 0.001 0.004
 Absent 11 (6.8) 85 (52.5)
Eye Rednessa
 Present 23 (14.2) 32 (19.8) 0.38 (0.24,0.53) <0.001 <0.001
 Absent 8 (4.9) 99 (61.2)
Burninga,b
 Present 6 (3.7) 37 (23.0) 0.13 (−0.01,0.27) <0.001 <0.001
 Absent 5 (3.1) 113 (70.1)
Itchinga
 Present 6 (3.7) 26 (16.0) 0.18 (0.01,0.36) <0.001 0.002
 Absent 6 (3.7) 124 (76.6)
Grittya
 Present 13 (8.0) 27 (16.7) 0.26 (0.09,0.43) 0.016 0.033
 Absent 12 (7.4) 110 (68.0)
Sensitive to Lighta
 Present 16 (9.9) 56 (34.5) 0.17 (0.05,0.28) <0.001 <0.001
 Absent 6 (3.7) 84 (51.8)

ESQ, Eye Symptom Questionnaire; MR, Medical Record; CI, Confidence Interval; freq, frequency

p <0.001 for all eight symptoms, McNemar’s test

a

“Present” reported as “somewhat/very much of a problem” in at least one eye and “Absent” reported as “no problem at all/a little bit of a problem” in both eyes for the symptom

b

Missing data was present for these symptoms, percentages based on: n=160 subjects for Blurry vision and Burning

c

“Present” reported as “moderate/severe/very severe” in at least one eye and “Absent” reported as “none/mild” in both eyes for the symptom

d

Symptoms were “Present” if documented in the medical record for the subject

e

Symptoms were “Absent” if documented as no symptom in the MR or not documented in the MR