Table 3. IVF cycle characteristics according to hCG dose and patient age.
| hCG (IU) | 10,000 | 5,000 | 4,000 | 3,300 |
|---|---|---|---|---|
| Age < 35 y | ||||
| # of patients | 1,333 | 802 | 516 | 280 |
| # of prior IVF attempts | 1.9 ±2.0 | 1.8±2.0 | 1.5±1.6 | 1.4±1.7 |
| # of mature oocytes | 8.0±4.3 | 11.1±4.8 | 12.1±5.2 | 13.0±5.6 |
| fertilization rate (%) | 73.4±24.7 | 69.7±23.8 | 69.8±24.9 | 72.1±23.2 |
| # of embryos transferred | 2.1±0.6 | 2.2±0.6 | 2.2+0.6 | 2.2±0.5 |
| E2/MII ratio * | 186±139 | 226±210 | 260±225 | 312±327 |
| Blastocyst transfer (%) * | 16.3 | 24.8 | 31.9 | 33.6 |
| Age 35–37 y | ||||
| # of patients | 1,042 | 559 | 291 | 150 |
| # of prior IVF attempts | 2.3±2.1 | 2.2±2.1 | 2.1±2.0 | 2.1±1.8 |
| # of mature oocytes | 6.7±3.9 | 9.9±4.5 | 11.4±4.8 | 12.5±5.6 |
| fertilization rate (%) | 73.7±25.6 | 72.8±22.4 | 73.9±21.6 | 70.6±25.0 |
| # of embryos transferred | 2.6±0.9 | 2.7±0.9 | 2.8±0.9 | 2.7±0.9 |
| E2/MII ratio * | 221±164 | 240±147 | 271±201 | 327±295 |
| Blastocyst transfer (%) * | 9.0 | 18.9 | 23.7 | 26.8 |
| Age 38–40 y | ||||
| # of patients | 1,540 | 550 | 270 | 119 |
| # of prior IVF attempts | 2.9±2.6 | 2.6±2.1 | 2.5±2.3 | 2.4±2.2 |
| # of mature oocytes | 5.8±3.5 | 9.5±4.5 | 10.7±4.7 | 11.8±5.2 |
| fertilization rate (%) | 73.0±26.6 | 72.8±23.8 | 70.9±23.5 | 69.3±23.2 |
| # of embryos transferred | 3.0±1.2 | 3.3±1.2 | 3.4±1.1 | 3.2±1.1 |
| E2/MII ratio * | 235±158 | 260±174 | 293±190 | 369±395 |
| Blastocyst transfer (%) * | 5.8 | 14 | 15.3 | 22.2 |
| Age 41–42 y | ||||
| # of patients | 1,076 | 336 | 156 | 70 |
| # of prior IVF attempts | 3.1±3.0 | 3.0±2.4 | 3.1±2.8 | 2.5±2.2 |
| # of mature oocytes | 5.5±3.4 | 8.9±4.0 | 10.4±4.8 | 10.6±4.6 |
| fertilization rate (%) | 72.2±27.3 | 71.8±23.6 | 71.9±23.0 | 76.4±20.7 |
| # of embryos transferred | 3.1±1.5 | 3.8±1.5 | 4.1±1.5 | 4.1±1.4 |
| E2/MII ratio * | 254±183 | 290±229 | 337±364 | 357±220 |
| Blastocyst transfer (%) * | 4.6 | 9.7 | 9.5 | 10.4 |
| Age >42 y | ||||
| # of patients | 810 | 220 | 102 | 30 |
| # of prior IVF attempts | 3.5±3.2 | 3.2±2.3 | 3.1±2.4 | 2.8±3.1 |
| # of mature oocytes | 4.9±3.1 | 8.9±4.0 | 10.8±5.4 | 11.0±4.6 |
| fertilization rate (%) | 70.0±28.6 | 73.4±22.0 | 75.1±19.3 | 66.6±20.9 |
| # of embryos transferred | 3.1±1.7 | 4.5±1.8 | 4.8±1.8 | 4.7±1.8 |
| E2/MII ratio * | 256±171 | 294±251 | 326±333 | 319±183 |
| Blastocyst transfer (%) * | 2.8 | 7.6 | 10.6 | 6.7 |
* p < 0.05