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. 2017 Apr;10(4):37–46.

Table 5.

Merkel cell carcinoma global guideline comparison of surgical margins44,46–48

ORGANIZATION PERIPHERAL MARGINS DEEP MARGINS
NCCN Preferred: WLE
-1–2cm
Alternative: MMS (provided it does not interfere with SNLB when indicated)		 Level of investing fascial layer
EDF Preferred: MMS
-1–2cm		 Not specified
Denmark Preferred: WLE
-2–3cm
Alternative: MMS		 Level of underlying fascia
German Preferred: WLE
-3cm
Alternative: MMS		 Not specified

European Dermatology Forum (EDF), National Cancer Care Network (NCCN), Mohs micrographic surgery (MMS), sentinel lymph node biopsy (SNLB), wide local excision (WLE)