Table 4.

Multivariable‐Adjusted Hemodynamic Correlates of Brachial and Carotid Pulse Pressures

Hemodynamic	Total Sample (N=3762)			Nonmedicated (n=1204)
Parameter	Coefficient (SE)	Partial R 2	P Value	Coefficient (SE)	Partial R 2	P Value
Brachial pulse pressure
cfPWV	0.01 (0.0006)	0.083	<.0001	0.01 (0.001)	0.069	<.0001
SV index	2.22 (0.20)	0.030	<.0001	1.90 (0.34)	0.024	<.0001
AIx	2.14 (0.20)	0.030	<.0001	1.90 (0.33)	0.026	<.0001
LVEF	0.74 (0.20)	0.004	.0002	0.04 (0.33)	0.00001	.90
ET	4.03 (0.18)	0.112	<.0001	3.11 (0.33)	0.063	<.0001
UT	−1.31 (0.19)	0.011	<.0001	−1.29 (0.34)	0.011	.0001
Carotid pulse pressure
cfPWV	0.01 (0.001)	0.042	<.0001	0.014 (0.002)	0.045	<.0001
SV index	3.51 (0.31)	0.032	<.0001	2.73 (0.49)	0.023	<.0001
AIx	2.42 (0.31)	0.016	<.0001	2.03 (0.48)	0.014	<.0001
LVEF	1.38 (0.30)	0.005	<.0001	0.45 (0.48)	0.0007	.36
ET	6.51 (0.27)	0.122	<.0001	5.20 (0.48)	0.082	<.0001
UT	−1.46 (0.30)	0.006	<.0001	−1.30 (0.49)	0.005	.008

Abbreviations: AIx, augmentation index; cfPWV, carotid‐femoral pulse wave velocity; ET, ejection time; LVEF, left ventricular ejection fraction; SV, stroke volume; UT, upstroke time.

All analyses were adjusted for age, sex, black race, body mass index, diabetes, and current smoking status. Coefficients represent change in pulse pressure per 1‐standard deviation change in the hemodynamic parameter.