Table 5.

Multivariable‐Adjusted Hemodynamic Correlates of Brachial and Carotid Pulse Pressures in the Total Sample (N=3762), by Age Group

Parameter	Age <75 y			Age 75–<80 y			Age ≥80 y
	Coefficient (SE)	Partial R 2	P Value	Coefficient (SE)	Partial R 2	P Value	Coefficient (SE)	Partial R 2	P Value
Brachial PP
cfPWV	0.01 (0.0009)	0.100	<.0001	0.01 (0.001)	0.077	<.0001	0.01 (0.001)	0.072	<.0001
SV index	1.78 (0.27)	0.020	<.0001	2.62 (0.38)	0.044	<.0001	3.03 (0.48)	0.051	<.0001
AIx	1.59 (0.26)	0.018	<.0001	2.50 (0.38)	0.043	<.0001	2.88 (0.52)	0.044	<.0001
LVEF	0.21 (0.28)	0.0003	.44	1.43 (0.35)	0.016	<.0001	1.24 (0.45)	0.010	.006
ET	3.66 (0.25)	0.093	<.0001	3.72 (0.034)	0.104	<.0001	5.06 (0.40)	0.178	<.0001
UT	−0.84 (0.26)	0.005	.002	−1.68 (0.36)	0.021	<.0001	−2.03 (0.46)	0.026	<.0001
Carotid PP
cfPWV	0.02 (0.001)	0.055	<.0001	0.01 (0.002)	0.033	<.0001	0.01 (0.002)	0.041	<.0001
SV index	2.88 (0.42)	0.22	<.0001	3.94 (0.59)	0.040	<.0001	4.73 (0.69)	0.057	<.0001
AIx	1.80 (0.40)	0.010	<.0001	2.66 (0.60)	0.019	<.0001	3.34 (0.75)	0.027	<.0001
LVEF	0.47 (0.43)	0.0005	.28	2.60 (0.54)	0.021	<.0001	2.04 (0.65)	0.013	.002
ET	6.16 (0.38)	0.107	<.0001	6.18 (0.52)	0.113	<.0001	7.26 (0.57)	0.169	<.0001
UT	−0.77 (0.41)	0.002	.06	−2.21 (0.56)	0.014	<.0001	−2.14 (0.65)	0.014	.001

Abbreviations: AIx, augmentation index; cfPWV, carotid‐femoral pulse wave velocity; ET, ejection time; LVEF, left ventricular ejection fraction; PP, pulse pressure; SV, stroke volume; UT, upstroke time.

All analyses were adjusted for age, sex, black race, body mass index, and current smoking status. Coefficients represent change in pulse pressure per 1‐standard deviation change in the hemodynamic parameter.