Table 2.
Clinicopathological features | Cases | MiR-101-2 expression | P value | ||
---|---|---|---|---|---|
Low | High | ||||
Age | ≥50 | 563 | 287 | 276 | 0.150 |
<50 | 218 | 104 | 114 | ||
Gender | Female | 772 | 385 | 387 | 0.485 |
Male | 9 | 6 | 3 | ||
T | T1–T2 | 657 | 343 | 314 | 0.008 |
T3–T4 | 123 | 48 | 75 | ||
N | N0 | 373 | 200 | 173 | 0.029 |
N1–N3 | 398 | 187 | 211 | ||
M | M0 | 610 | 343 | 267 | 0.017 |
M1 | 9 | 2 | 7 | ||
Stage | I–II | 587 | 298 | 289 | 0.129 |
III–IV | 186 | 88 | 98 | ||
ER | Positive | 565 | 275 | 290 | 0.058 |
Negative | 170 | 88 | 82 | ||
PR | Positive | 502 | 245 | 257 | 0.250 |
Negative | 231 | 118 | 113 | ||
HER2 | Positive | 99 | 54 | 55 | 0.481 |
Negative | 397 | 207 | 190 |
T – tumor stage; N – lymph node stage; M – metastasis stage; ER – estrogen receptor; PR – progesterone receptor; HER2 – human epidermal growth factor receptor 2. The median was chosen as the cut-off value because of the skewed distribution of the expression data.