Fig 4. Loss of pericyte coverage correlates with capillary reductions in the cortex and hippocampus of adult PdgfrβF7/F7 (F7/F7) mice.
(A-C) Correlations between age-dependent reduction in capillary length and loss of pericyte coverage in the somatosensory cortex S1 region (S1Cx) (A), the CA1 region of the hippocampus (Hp) (B), and posterior thalamus (Thal) (C) in F7/F7 mice. Single data points were from 4-6- (grey), 12–16 (red), and 36–48 (blue) week-old F7/F7 mice (n = 15 individual points; each point represents the mean value per mouse calculated as explained in Fig 1 legend and Methods). r = Pearson’s coefficient. P, significance.