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. Author manuscript; available in PMC: 2017 Jul 26.
Published in final edited form as: Nature. 2017 Jan 18;541(7638):481–487. doi: 10.1038/nature21029

EXTENDED DATA FIGURE 4. Screen for A1 reactive mediators.

EXTENDED DATA FIGURE 4

Fold change data from published microarray datasets of A1 (neuroinflammatory) reactive astrocytes (panel a), and microfluidic qPCR analysis of purified astrocytes treated with lipopolysaccharide (LPS)-activated microglia conditioned media (panel b), non-activated microglia conditioned media (panel c), Il-1α, TNFα and C1q (panel d), LPS-activated microglia conditioned media pre-treated with neutralizing antibodies to Il-1α, TNFα and C1q (panel e), astrocytes treated with Il-1α, TNFα and C1q and post-treated with FGF (panel f), microglia conditioned media activated with interferon gamma (IFNγ, panel g), and with TNFα (panel h). N = 6 per experiment. Error bars indicate s.e.m.