Extended Data Table 5.
Clinical and pathological characteristics of human post mortem tissue samples from Parkinson’s disease patients and age-matched controls.
| Sex | Age (years) | Race | PMD (hours) | FDX | CERAD | BRAAK | Brain region |
|---|---|---|---|---|---|---|---|
| M | 76 | W | 18 | PD | 0 | 2 | SN |
| M | 86 | W | 19 | Lewy body disease, incipient AD | 0 | 2 | SN |
| M | 90 | W | 7 | PD, neurofibrillary tangles and tau pathology BRAAK 4, TBI possible | 0 | 4 | SN |
| M | 92 | W | 17 | PD, dementia | 0 | 3 | SN |
| M | 80 | W | 9.5 | PD, dementia | 0 | 3 | SN |
| F | 85 | W | 19 | PD, dementia, FTD, cerebrovascular disease | 0 | 4 | SN |
| M | 76 | W | 13.5 | PD | 0 | 1 | SN |
| M | 76 | W | 25 | Control | NA | NA | SN |
| M | 82 | W | 20 | Control | NA | NA | SN |
| M | 81 | W | 26 | Control | NA | NA | SN |
| M | 76 | W | 9 | Control | NA | NA | SN |
| M | 83 | W | 25 | Control, vascular disease | NA | NA | SN |
Abbreviations: AD, Alzheimer’s disease; BRAAK, Braak staging10; CERAD, Consortium to Establish a Registry for Alzheimer’s Disease (CERAD) neurocognitive test battery result; F, female; FDX, functional diagnosis; FTD, Frontotemporal dementia; M, male; PMD, post mortem delay; SN, substantia nigra; NA, not applicable; TBI, traumatic brain injury; W, white (Caucasian).