Table 3.

Knockout of ADAR1 or ADAR1p150 from WT, MAVS KO, RNASEL KO, PKR KO, NS2-WT or NS2^H126R –WT cells.

DOI: http://dx.doi.org/10.7554/eLife.25687.010

Genotype of parent cells	sgRNA	Resulting KO cells
		Name	Number of clones screened	Number of KO clones obtained
WT	sgADAR1-6	p150 KO	24	12
	sgADAR1-4	NA*	17	0
MAVS KO	sgADAR1-6	MAVS-p150 KO	24	8
	sgADAR1-4	MAVS-ADAR1 DKO	23	8
RNASEL KO	sgADAR1-4	RNASEL-ADAR1 DKO	24	2
PKR KO	sgADAR1-4	NA	24	0
WT NS2	sgADAR1-4	NS2-ADAR1 KO	56	4
WT NS2H126R	sgADAR1-4	NA	54	0

*NA, Not available.