Skip to main content
. Author manuscript; available in PMC: 2017 Sep 13.
Published in final edited form as: Nat Neurosci. 2017 Mar 13;20(5):700–707. doi: 10.1038/nn.4526

Figure 8. Restraint stress and C1 neuron stimulation produce opposite effects on arterial pressure and heart rate.

Figure 8

(a) Effect of restraint stress on arterial pressure (AP) and heart rate (HR) in a DBH-cre mouse. (b and c) Mean AP and HR before (Pre), during and after (Post) restraint (each period: 10 min) in DBH-cre mice (n = 4). Statistics: one-way repeated measures ANOVA with Tukey–Kramer test; [F(2, 9) = 29.11, P = 0.0001] (b) and [F(2, 9) = 21.93, P = 0.0003] (c). * vs. Pre. Double symbols, P < 0.01 and triple symbols, P < 0.001. (d) Effect of C1 stimulation (10 ms, 5 Hz, 10 min) on arterial pressure (AP) and heart rate (HR) in a DBH-cre mouse. (e and f) Effect of C1 neuron stimulation (laser 5 Hz) on AP and HR in DBH-cre mice. Mean AP and HR before (Pre), during and after (Post) C1 neuron stimulation (each period: 10 min) (n = 4/group). Statistics: one-way repeated measure ANOVA with Tukey–Kramer test; [F(2, 9) = 12.7, P = 0.0024] (e) and [F(2, 9) = 9.249, P = 0.0066] (f). * vs. Pre. Single symbols, P < 0.05 and double symbols, P < 0.01.