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. Author manuscript; available in PMC: 2018 Apr 1.
Published in final edited form as: Microcirculation. 2017 Apr;24(3):10.1111/micc.12364. doi: 10.1111/micc.12364

Figure 5. Effect of 1400W on the TNF-α-induced decrease in lymphatic contraction frequency.

Figure 5

A. Original recordings comparing the contractile activity of lymphatic vessels pressurized at 5 cmH2O after a 24-h incubation in DMEM/F12 media (sham), in media plus 3 ng/ml TNF-α and in media/TNF-α plus 10 μM 1400W. Time scale bar applies to all traces. B. Summary bar graph of the effect of 1400W on TNF-α-induced decreased response relative to the contraction frequency measured in the respective sham vessels (n=5; *P<0.05 vs own sham, paired Student t-test and ##P<0.01, repeated measures of ANOVA with Bonferroni’s post-hoc test. C. Summary bar graph of the absence of effect of a 24-h incubation with 10 μM indomethacin on TNF-α-induced decreased response relative to the contraction frequency measured in the respective sham vessels (n=4).