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AAV-mediated CatB transduction increases Lamp1 expression in the hippocampus of APP/PS1 mice and cultured neurons. a Immunoblot of Lamp1 in intracellular fraction of the mouse hippocampus. b Quantification of Lamp1 expression (n = 6). c Confocal microscopy shows cellular localization of Lamp1 lysosomal compartment (red) in neurons. d Lamp1 expression levels were quantified using ImageJ (n = 3). Bars represent mean ± S.E.M. *p < 0.05, **p < 0.01, one-way ANOVA, Newman-Keuls post hoc test
