Fig. 5.

Vaccination reduces naïve T cell depletion following infection. a, naïve CD4 + T cells were enumerated based on negative staining for CD95- and positive staining for CD28 in pre-challenge (cf. Fig. 2a) and 60 dplc (days post last challenge, cf. Fig. 2a). b, naïve CD8 + T cells were enumerated based on positive staining for CD45RA and CCR7 in pre-challenge and 60 dplc blood samples. Shown are individual animals with brackets to indicate that only infected vaccinees are included in the statistical comparisons. Vaccinated animals are grouped as indicated based on their levels of acute viremia.