Table 1.
Univariate and multivariate analysis for associations between DHX32 expression and patient features of colorectal cancer.
| Feature | n | Univariate analysis |
Multivariate analysis |
||||||
|---|---|---|---|---|---|---|---|---|---|
| OR | 95%CI | P | OR | 95%CI | P | ||||
| Gender | |||||||||
| Male | 78 | 1 | |||||||
| Female | 61 | 0.99 | 0.45 | 2.15 | 0.975 | ||||
| Missing | 0 | ||||||||
| Age | |||||||||
| ≤ 50 | 37 | 1 | |||||||
| > 50 | 102 | 0.51 | 0.19 | 1.36 | 0.173 | ||||
| Missing | 0 | ||||||||
| T stage | |||||||||
| 1 + 2 + 3 | 30 | 1 | |||||||
| 4 | 94 | 1.06 | 0.4 | 2.81 | 0.91 | ||||
| Missing | 15 | ||||||||
| Histologic grade | |||||||||
| Well | 22 | 1 | 1 | ||||||
| Poor/moderate | 110 | 4.24 | 1.62 | 11.09 | 0.002 | 3.79 | 1.32 | 10.85 | 0.013* |
| Missing | 7 | ||||||||
| Lymphatic invasion | |||||||||
| Absent | 73 | 1 | 1 | ||||||
| Present | 51 | 3.24 | 1.21 | 8.69 | 0.016 | 2.38 | 0.84 | 6.7 | 0.102 |
| Missing | 15 | ||||||||
| Distant metastasis | |||||||||
| Absent | 98 | 1 | 1 | ||||||
| Present | 25 | 4.15 | 0.92 | 18.85 | 0.049 | 2.24 | 0.46 | 10.91 | 0.317 |
| Missing | 16 | ||||||||
| Perineural invasion | |||||||||
| Absent | 44 | 1 | |||||||
| Present | 90 | 1.8 | 0.78 | 4.15 | 0.165 | ||||
| Missing | 5 | ||||||||
| Vascular invasion | |||||||||
| Absent | 60 | 1 | |||||||
| Present | 76 | 1.9 | 0.85 | 4.23 | 0.114 | ||||
| Missing | 3 | ||||||||
n: sample number; OR: odd ratio; CI: confidence interval; P: P-value
Bold values indicate significance at P < 0.05.
⁎
Significant association between DHX32 expression and pathologic grades of CRC.