Table 3.
Discovery cohort: echocardiographic characteristics according to the absence or presence of LVH.
| Characteristic | All patients | No LVH | LVH | P value |
|---|---|---|---|---|
| n | 318 | 205 | 113 | |
| Echocardiographic parameters | ||||
| Cardiac structure | ||||
| LVMI (g/m2) | 98.5 ± 26.6 | 84.6 ± 18.9 | 123.8 ± 18.7 | < 0.0001 |
| LVH, n (%) | 113 (35) | 0 | 113 (100) | |
| Posterior wall thickness (cm) | 1.05 ± 0.15 | 1.00 ± 0.15 | 1.11 ± 0.14 | < 0.0001 |
| Septal wall thickness (cm) | 1.07 ± 0.15 | 1.03 ± 0.15 | 1.15 ± 0.14 | < 0.0001 |
| LVEDD (cm) | 4.9 ± 0.7 | 4.7 ± 0.7 | 5.3 ± 0.6 | < 0.0001 |
| LVESD (cm) | 3.1 ± 0.8 | 3.1 ± 0.8 | 3.2 ± 0.7 | 0.19 |
| Cardiac function | ||||
| Ejection fraction (%) | 68 ± 12 | 69 ± 10 | 68 ± 13 | 0.38 |
| E (m/s) | 0.82 ± 0.20 | 0.82 ± 0.19 | 0.82 ± 0.23 | 0.88 |
| A (m/s) | 0.89 ± 0.22 | 0.88 ± 0.22 | 0.91 ± 0.23 | 0.37 |
| E/A ratio | 0.95 ± 0.29 | 0.97 ± 0.30 | 0.90 ± 0.28 | 0.06 |
| Deceleration time (ms) | 229.4 ± 60.7 | 226.6 ± 57.5 | 234.2 ± 66.3 | 0.30 |
| e′ (m/s) | 0.09 ± 0.04 | 0.09 ± 0.04 | 0.08 ± 0.04 | 0.20 |
| E/e′ ratioa | 10.1 [7.2, 14.0] | 9.9 [7.1, 13.7] | 10.7 [7.6, 14.1] | 0.42 |
Data is expressed as mean ± SD.
a
Median [25th, 75th quartiles] or n (%). LVH, left ventricular hypertrophy; LVEDD, left ventricular end diastolic dimension; LVESD, left ventricular end systolic dimension; LVMI, left ventricular mass index.