Table 5.
a. Total levels of lipids in those with brain injuries and those with VAP. b. Lipoprotein subfractions whch were most discriminant in the OPLS-DA model with the relative concentrations in VAP compared to brain injury. P- and q-values are given for ANOVA with correction for false discovery rate. Concentrations given as mean ± standard deviation.
| a | |||
|---|---|---|---|
| Brain Injury | VAP | p-value | |
| N | 26 | 7 | – |
| Total triglycerides (mg/dL) | 152.0 ± 71.0 | 198.6 ± 53.3 | 0.08 |
| Total cholesterol (mg/dL) | 215.2 ± 75.1 | 185.3 ± 45.1 | 0.20 |
| LDL cholesterol (mg/dL) | 111.0 ± 65.1 | 77.6 ± 29.2 | 0.06 |
| HDL cholesterol (mg/dL) | 78.6 ± 24.5 | 46.1 ± 15.3 | < 0.001 |
| b | ||||
|---|---|---|---|---|
| Lipid species | Brain injury | VAP | p-Value | q-Value |
| N | 26 | 7 | – | – |
| IDCH in mg/dL | 9.7 ± 7.2 | 26.9 ± 6.5 | 3.1 × 10− 6 | 0.0003 |
| IDAB in mg/dL | 3.5 ± 2.5 | 8.7 ± 2.0 | 1.6 × 10− 5 | 0.001 |
| IDPL in mg/dL | 6.3 ± 4.2 | 14.8 ± 4.2 | 4.4 × 10− 5 | 0.002 |
| H2TG in mg/dL | 3.0 ± 1.3 | 5.3 ± 1.2 | 0.0002 | 0.005 |
| H3TG in mg/dL | 2.7 ± 1.3 | 5.0 ± 1.3 | 0.0002 | 0.005 |
| IDFC in mg/dL | 2.1 ± 2.2 | 5.8 ± 2.0 | 0.0004 | 0.007 |
| V5CH in mg/dL | 0.9 ± 1.0 | 3.0 ± 2.0 | 0.0006 | 0.007 |
| L1TG in mg/dL | 6.0 ± 4.4 | 13.5 ± 5.5 | 0.0006 | 0.007 |
| V4FC in mg/dL | 2.3 ± 2.0 | 5.8 ± 2.8 | 0.0007 | 0.007 |
| V5TG in mg/dL | 3.2 ± 1.6 | 5.9 ± 1.9 | 0.0008 | 0.007 |
| H4CH in mg/dL | 21.7 ± 7.9 | 9.2 ± 7.7 | 0.0008 | 0.007 |
| H4FC in mg/dL | 5.5 ± 2.1 | 2.3 ± 2.0 | 0.0010 | 0.009 |
| HDTG in mg/dL | 14.9 ± 6.1 | 23.9 ± 5.1 | 0.0012 | 0.009 |
| V4CH in mg/dL | 4.8 ± 4.1 | 11.7 ± 6.0 | 0.0013 | 0.009 |
| HDFC in mg/dL | 20.8 ± 7.4 | 10.5 ± 4.9 | 0.0016 | 0.011 |