Table 1.

Previously reported surface markers of human and mouse multipotent mesenchymal stromal/stem cells.

Cell surface marker	Human	Mouse	Distribution
CD11b/Integrin αM	−	−	Myeloid, macrophage, NK cells, T act, B subset
CD19/B4	−	−	B cells, follicular dendritic cells
CD29/Integrin β1	+	+	Leukocytes, fibroblasts, endothelium, epithelium
CD31/PECAM-1	−	−	Platelets, gran, endothelium, dendritic cells, mono subset, T subset, B subset, lymphokine-activated killer cell
CD34/Mucocialin	−	−	Hematopoietic precursors, capillary endothelium, bone marrow stromal cells, mast cells
CD44	+	+	Broad, memory T, fibroblast, epithelium, endothelium, cancer stem cells
CD45	−	−	Leukocytes, not mature erythrocytes
CD49a/Integrin αI	+	?	T act, endothelium
CD51/Integrin αV	+	+	Platelets, megakaryocytes, endothelium, osteoblasts, melanoma
CD56/NCAM-1	+	+	Neural tissue, multiple isoforms
CD73/5′-Nucleotidase	+	+	T subset, B subset, follicular dendritic cells, endothelium, bone marrow stromal cells
CD90/THY1	+	+	Thymocytes, T cells, hematopoietic subset, neurons
CD105/Endoglin	+	+	Endothelium, bone marrow cell subset, mac act
CD106/VCAM-1	+	+	Endothelium act, follicular dendritic cells, bone marrow myeloid
CD117/c-Kit	+	?	Hematopoietic stem and progenitors, neural crest-derived melanocytes, primordial germ cells, mast cells
CD140α/PDGFRα	+	+	Fibroblasts, smooth muscle, glial cells, chondrocytes
CD140β/PDGFRβ	+	+	Fibroblasts, smooth muscle, glial cells, chondrocytes
CD146/MCAM	+	?	Embryonic tissue, mammary tumors
CD166/ALCAM	+	+	Neurons, T act, mono, epithelium, fibroblasts
CD271/LNGFR	+	?	Neurons, mesenchymal stem cells
Nestin	+	+	Neural stem cells, glioma stem cells
Stro-1	+	?	Mesenchymal stem cells
Sca-1	?	+	Bone marrow hematopietic stem cells and precursors, bone marrow mesenchymal stem cells

+: positive selection, −: negative selection, ?: unknown.