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. 2017 Apr 7;18:216–224. doi: 10.1016/j.ebiom.2017.04.005

Table 2.

Associations between primary predictors and SI status.

Correlate N (case, control) OR 95% CI p-Value aORb 95% CI p-Value
Plasma neutralization breadth 13, 39 1.00 0.52–1.93 1.00 1.35 0.73–2.53 0.33
Plasma neutralization potency 13, 39 0.93 0.75–1.15 0.51 0.99 0.74–1.32 0.94
Plasma ADCC activity 20, 60 0.44 0.06–3.10 0.41 0.74 0.09–6.00 0.78
Cervical ADCC activity 17, 51 1.16 0.51–2.63 0.73 0.18 0.52–2.67 0.70
Plasma V1V2 IgG bindinga
 ZM109 20, 60 1.00 0.31–3.18 1.00 0.96 0.30–3.04 0.94
 ZM53 20, 60 0.89 0.24–3.33 0.89 0.97 0.26–3.63 0.96
 Case A2 20, 60 1.00 0.27–3.69 1.00 1.05 0.27–4.08 0.94
 Average 20, 60 0.79 0.48–1.29 0.34 0.64 0.20–2.06 0.46
Plasma gp140 IgA binding 20, 60 0.93 0.58–1.49 0.78 0.85 0.51–1.41 0.52

ADCC = antibody-dependent cell-mediated cytotoxicity, aOR = adjusted odds ratio, CI = confidence interval, OR = odds ratio, SI = superinfection, VL = viral load.

a

Dichotomized detectable vs. undetectable.

b

Adjusted for VL.