Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
ACMG Classification of Variants
A significantly higher prevalence of variants of unknown significance (VUS) was found in cardiomyopathy genes compared to primary electrical disease genes, and there was a highly unfavorable ratio of VUS to pathogenic and likely pathogenic variants in the cardiomyopathy genes (28:1) per the American College of Medical Genetics (ACMG) classification of 288 variants in 170 cases. P = pathogenic; LP = likely pathogenic.
