Table II.
Comparison of stimulation outcomes in the two study groups
| Variables |
LA group
(n=35) |
PA group
(n=35) |
p-value | CI 95% |
|---|---|---|---|---|
| Total gonadotropin /cycle (IU) | 2475 ± 266 | 2625± 531 | 0.34 | - 1.23 – 3.52 |
| Duration of stimulation (Day) | 10 ±0.70 | 10.2 ±0.837 | 0.87 | - 0.93 – 1.33 |
| Peak E2 level at trigger (pg/m L ) | 808 ± 173 | 693 ±199 | 0. 36 | -3.86 – 15.84 |
| Serum progesterone at trigger (ng/m L) | 0.5 ± 0.3 | 0.6 ± 0.1 | 0.12 | -0.7 - 1.1 |
| Endometrial thickness (mm ) | 8.89 ±0.458 | 8.70±0.489 | 0.10 | -0.41 – 0.03 |
| Follicles ≥16 mm ( n) | 3.4 ± 0.1 | 3.1 ± 0.7 | 0.08 | -0.23 – 0.36 |
| Oocyte retrieved (n) | 2.80 ± 1.09 | 2.60±1.51 | 0.81 | -2.12 – 1.72 |
| Metaphase II oocytes (n) | 2.03 ± 0.12 | 2.09 ± 0.13 | 0.84 | -0.52 - 0.63 |
| Good quality embryo (%) | 37.1 | 36.8 | 0.42 | -0.42-1.21 |
| Embryos transferred (n) | 1.2± 0.75 | 1.23 ± 0.74 | 0.82 | -0.35 - 0.41 |
| Fertilization ratea (%) | 72.2 | 69.3 | 0.22 | ──── |
Values are expressed as mean±SD or percentage (%). p-value ≤ 0.05 was considered statistically significant.
Groups compared using independent Student’s t test unless noted (a Chi-square was used). 95% CI: 95% confidence interval
E2= Estradiol
LA: Letrozole+Antagonist
PA= Placebo+Antagonist