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. 2017 Mar 28;140(5):1238–1251. doi: 10.1093/brain/awx069

Figure 2.

Figure 2

Correlation of QST findings and severity of RDEB disease. Pearson’s correlation analyses were performed to explore associations between findings on the quantitative sensory profile and the severity of RDEB measured using the Birmingham severity score (BEBS). (A) The correlation coefficient (r = −0.64) showed that there was a negative correlation between cold detection threshold (CDT) and severity of RDEB disease. This correlation was highly significant (P = 0.005), n = 29 patients. (B) The correlation coefficient (r = −0.78) showed that there was a negative correlation between warm detection threshold (WDT) and severity of RDEB disease. This correlation was highly significant (P < 0.001), n = 29 patients. (C) The correlation coefficient (r = −0.58) showed that there was a negative correlation between thermal sensory limen (TSL) and severity of RDEB disease. This correlation was highly significant (P = 0.002), n = 29 patients. (D) The correlation coefficient (r = −0.61) showed that there was a negative correlation between heat pain threshold (HPT) and severity of RDEB disease. This correlation was highly significant (P = 0.001), n = 29 patients. (E and F) There was no significant correlation between the mechanical pain sensitivity and the wind up ratio and the severity of disease (r = 0.003, r = 0.16, respectively) n = 29 patients.