TABLE 1.
Patient baseline demographics
| Patient demographic | Preintervention (n = 116) | Intervention (n = 123) | P value |
|---|---|---|---|
| Mean age (yr) ± SD (n) | |||
| All | 58.33 ± 28.3 | 63.5 ± 23.4 | 0.219 |
| Adult | 68.43 ± 17.8 (97) | 68.59 ± 16.4 (113) | 0.946 |
| Pediatric | 6.78 ± 7.5 (19) | 6 ± 6.5 (10) | 0.783 |
| No. (%) of females | 63 (54.3) | 66 (53.7) | 0.920 |
| No. (%) with following clinical status: | |||
| General medicine | 77 (66.3) | 82 (66.7) | 0.962 |
| ICU | 39 (33.6) | 41 (33.3) | 0.962 |
| Hospice or palliative care consult | 12 (10.3) | 22 (17.9) | 0.095 |
| Mean Pitt bacteremia score ± SD | 1.91 ± 1.96 | 2.39 ± 2.44 | 0.096 |
| No. (%) with hemodynamic instability requiring vasopressors | 20 (17.2) | 19 (15.4) | 0.708 |
| Mean Charlson comorbidity index ± SD | 4.81 ±3.76 | 5.15± 3.47 | 0.468 |
| No. (%) with following no. of MDRO risk factorsa | |||
| 0 | 23 (19.8) | 27 (21.9) | 0.558 |
| 1 | 29 (25) | 39 (31.7) | |
| 2 | 29 (25) | 29 (23.6) | |
| 3 | 21 (18.1) | 20 (16.3) | |
| 4 | 10 (8.6) | 7 (5.7) | |
| 5 | 4 (3.4) | 1 (0.8) | |
| No./total (%) with MDRO infections | 27/113 (25.3) | 21/83 (23.9) | 0.996 |
| No. (%) of organisms | |||
| All Gram positive | 56 (44.4) | 78 (61.9) | 0.005 |
| Gram-positive infection | 43 (76.8) | 35 (44.9) | 0.340 |
| Gram-positive contaminant | 13 (23.2) | 43 (55.1) | <0.001 |
| Gram negative | 59 (46.8) | 46 (36.5) | 0.097 |
a
MDRO risk factors include health care exposure (recent hospitalization for >48 h or nursing home/skilled nursing facility residence), prior antimicrobial (especially broad spectrum) use within 90 days, recent history of MDRO, hospitalization for >5 days, mechanical ventilation for ≥5 days, immunosuppression, chronic dialysis within 30 days, a recent invasive procedure, home wound care, intravenous drug use, and structural lung disease.