Table 2.

The pathways incorporated by downregulated microRNAs in CAVD.

KEGG pathway	P value	Genes	miRNAs
Cell cycle	<1E − 16	48	19
PI3K-Akt signaling pathway	2.22E − 16	95	17
ECM-receptor interaction	1.85E − 12	9	4
HIF-1 signaling pathway	8.63E − 10	30	15
p53 signaling pathway	1.49E − 08	28	14
ErbB signaling pathway	7.14E − 05	23	12
Neurotrophin signaling pathway	0.00249	19	10
Focal adhesion	0.0029	19	6
DNA replication	0.013417	19	2