Table 2.

Summary of the Self‐Dissociation Constants of Wild‐Type and Mutant BECN2 CCD

BECN2 CCD	K d (μM)	dH (kJ/mol)	dS (J/K mol)
Wild type	138 ± 6	120.7 ± 7.4	492.7 ± 25.4
E173L	5180 ± 940	205.6 ± 12.4	757.2 ± 41.6
N187L	0.04 ± 0.01	−877.8 ± 89.9	−2904.7 ± 311.4
A190L + Y215L	104 ± 9	−85.4 ± 1.4	−220.0 ± 4.2
A197L + E208L	Not detectable
H211L	13.3 ± 2.2	168.2 ± 1.1	677.4 ± 5.1
Q222L	4800 ± 750	98.5 ± 9.1	386.3 ± 32.6
R243L	326 ± 4	165.3 ± 7.6	640.6 ± 26.5