Table 4.

Summary of Thermodynamic Parameters for Binding of Wild‐Type and Mutant Beclin 2 CCDs to Atg14 CCD

Beclin 2 CCD	K d (μM)	dH (kJ/mol)	dS (J/K·mol)
Wild type	0.22 ± 0.04	−162.2 ± 1.1	−435.4 ± 2.2
E173L	0.58 ± 0.14	−154.3 ± 6.8	−416.0 ± 21.4
N187L	0.72 ± 0.11	−110.5 ± 16.1	−265.8 ± 57.1
A190L + Y215L	0.30 ± 0.02	−120.7 ± 3.9	−294.0 ± 13.8
A197L + E208L	1.23 ± 0.06	−61.7 ± 11.5	−100.9 ± 40.4
H211L	0.80 ± 0.18	−105.7 ± 3.0	−250.0 ± 12.2
Q222L	0.79 ± 0.01	−149.7 ± 0.1	−402.7 ± 0.2
R243L	0.54 ± 0.05	−148.7 ± 0.6	−396.0 ± 1.6